Doctors, Patients Raise Alarms About Cancer Linked to Breast Implants

Women choose to get breast implants either for breast reconstruction after mastectomy or for cosmetic reasons. The American Society of Plastic Surgeons reported 400,000 breast implant procedures took place in 2017, up nearly 40 percent since 2000.

It’s taken several years to gather data but the FDA now believes that textured breast implants may be more likely to cause ALCL, although it says smooth implants are also linked to an increased risk. The trouble is that there’s no organized effort to put together data from people who have implants and those who have developed ALCL.

Dermatologists Debunk Common Misconceptions About Laser Hair Removal

When performed by a doctor, laser hair removal is a safe, effective, and permanent solution for removing unwanted face and body hair. This clinically tested, FDA-approved treatment has been around since the mid-1990s and is a very common procedure among young adults ages 20 to 45. However, the results don’t occur overnight, say dermatologists from the American Academy of Dermatology, and in inexperienced hands, laser hair removal can be dangerous.

Performed improperly, the treatment can result in burns, permanent skin color changes, and even scars. To reduce the risk of possible side effects and ensure an effective treatment, the AAD recommends that consumers only seek laser hair removal from a medical doctor who is extremely skilled in using lasers and has in-depth knowledge of the skin.

For more information and to read the full press release, visit American Academy of Dermatology.

Revance Therapeutics Inc Announces Study Results and a License Agreement for RT002

Revance Therapeutics Inc, a Newark, Calif-based developer of neuromodulators for the treatment of aesthetic and therapeutic conditions, announces two pieces of company news regarding RT002.

RT002 is the Newark, Calif-based company’s long-acting neuromodulator DaxibotulinumtoxinA for Injection.

First, Revance shares SAKURA Phase 3 study results of RT002.

And second, the company announces it has entered into a license agreement with Fosun Pharma to market RT002 in China.

For more information, visit Revance Therapeutics Inc.

[Source(s): Revance Therapeutics Inc, Business Wire]

Does Hormone Therapy Fight Wrinkles Too?

Menopause: the time that marks the end of a woman’s menstrual cycle and the word so many of us don’t want to hear. Hot flashes, thin, dry skin, emotional highs and lows—the symptoms vary greatly from person to person, but unfortunately there’s currently no way to prevent menopause, which is why many women experiment with treatments like hormone replacement therapy (HRT) to find some relief.

Although the treatments are often linked to dangerous side effects, they’re also sometimes touted as a wrinkle-fighting solution for younger-looking skin, which has piqued the interest of researchers, as well as doctors and dermatologists. Here, we asked our experts to weigh in.

Read the full article at www.newbeauty.com

RealSelf Releases 2018 Aesthetics Trend Report and 2019 Watch List

RealSelf, an online marketplace to help people learn about cosmetic treatments and connect with doctors and other clinicians, reveals the latest annual trends related to consumer interest in elective cosmetic treatments. The RealSelf 2018 Aesthetics Trend Report was compiled by analyzing user behavior trends from U.S. consumers researching on RealSelf during 2018.

RealSelf analysts and medical experts have also released what they predict will be big trends in 2019.

To read the full press release about the 2018 Aesthetics Trend Report and the 2019 Aesthetics Watch list, visit www.prnewswire.com.

10 Skin-Care Products You’re Wasting Your Money On, According to Dermatologists

Before you spend all that cash on creams, serums, and toners, make sure you’re getting ones that actually work. Unfortunately, there are some pricey products out there that don’t do very much for your skin — and can actually end up irritating it.

So what are these products? INSIDER spoke to board-certified dermatologists to find out which items aren’t worth the money.

TIGR Matrix Offers Improved Reconstruction Outcomes, Study Suggests

Use of the synthetic and fully resorbable TIGR Matrix surgical mesh helped improve the outcome in breast cancer patients undergoing immediate reconstruction, according to a study published in the Journal of Plastic Surgery and Hand Surgery.

The TIGR Matrix and other surgical meshes aim to support, and hold in place, breast implants to improve the aesthetic result with decreased risk of capsule formation. However, traditional meshes, such as the biological acellular dermal matrices, have been linked to severe complications including seroma, necrosis, and the loss of implants.

In the study, lead author Hakan Hallberg and colleagues investigated the use of the TIGR Matrix in a prospective series of 49 consecutive patients undergoing immediate breast reconstruction with a tissue expander or permanent implant. All patients were non-obese, current non-smoker, and not scheduled for postoperative radiotherapy, explains a media release from Novus Scientific.

The TIGR Matrix—produced by Novus Scientific AB, headquartered in Uppsala, Sweden—resulted in a low incidence of complications. The rate of implant-loss was similar as reported with other matrices. Furthermore, TIGR Matrix showed a 3.1% incidence rate of seroma and a 1.5% risk of infections. For comparison, the reported incidences of seroma and infection with other matrices are up to 15% and 30%, respectively.

Immediate breast reconstruction with a tissue expander and TIGR Matrix surgical mesh has a low complication rate, concluded the investigators of the Sahlgrenska University Hospital in Gothenburg, Sweden, per the release.

[Source(s): Novus Scientific, PR Newswire]

Fiancé of Texas Woman Who Died After Plastic Surgery in Mexico Wants Doctors Charged with Murder

Following the death of his fiancé Laura Avila, who suffered severe brain damage after seeking plastic surgery in Mexico last month, Enrique Cruz is seeking legal action against the doctors responsible.

Avila, a 36-year-old woman from Dallas, Texas, was put on life support earlier this month after her family claims doctors at Rino Center in Ciudad Juarez, Mexico, allegedly placed anesthesia incorrectly in her spine before a procedure at the end of October.

NYU Researchers Report Ability to Regrow Hair on Wounded Skin

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By stirring crosstalk among skin cells that form the roots of hair, researchers report they have regrown hair strands on damaged skin.

The findings better explain why hair does not normally grow on wounded skin, and may help in the search for better drugs to restore hair growth, say the study’s authors in a media release.

Led by researchers at NYU School of Medicine and published recently in the journal Nature Communications, the study examined the effect of distinct signaling pathways in damaged skin of laboratory mice. Experiments focused on cells called fibroblasts that secrete collagen, the structural protein most responsible for maintaining the shape and strength of skin and hair.

As part of their investigation, researchers activated the sonic hedgehog signaling pathway used by cells to communicate with each other. The pathway is known to be very active during the early stages of human growth in the womb, when hair follicles are formed, but is otherwise stalled in wounded skin in healthy adults. Researchers say this possibly explains why hair follicles fail to grow in skin replaced after injury or surgery, the release explains.

“Our results show that stimulating fibroblasts through the sonic hedgehog pathway can trigger hair growth not previously seen in wound healing,” says study senior investigator and cell biologist Mayumi Ito, PhD, an associate professor in the Ronald O. Perelman Department of Dermatology at NYU Langone Health.

Regrowing hair on damaged skin is an unmet need in medicine, Ito says, because of the disfigurement suffered by thousands from trauma, burns, and other injuries. However, her more immediate goal, she adds, is to signal mature skin to revert back to its embryonic state so that it can grow new hair follicles, not just on wounded skin, but also on people who have gone bald from aging.

Ito says scientists have until now assumed that, as part of the healing process, scarring and collagen buildup in damaged skin were behind its inability to regrow hair.

“Now we know that it’s a signaling issue in cells that are very active as we develop in the womb, but less so in mature skin cells as we age,” she adds in the release.

Key among the study’s findings was that no signs of hair growth were observed in untreated skin, but were observed in treated skin, offering evidence that sonic hedgehog signaling was behind the hair growth.

To bypass the risk of tumors reported in other experiments that turned on the sonic hedgehog pathway, the NYU Langone team turned on only fibroblasts located just beneath the skin’s surface where hair follicle roots (dermal papillae) first appear. Researchers also zeroed in on fibroblasts because the cells are known to help direct some of the biological processes involved in healing.

Hair regrowth was observed within 4 weeks after skin wounding in all treated mice, with hair root and shaft structures starting to appear after nine weeks.

Ito says her team plans further investigations into how chemical and genetic stimulants of fibroblasts might activate the sonic hedgehog pathway in wounded human skin. Her goal is to identify likely drug targets for hair regrowth, the release concludes.

[Source(s): NYU School of Medicine, PR Newswire]