Evolus Receives FDA Approval for Jeuveau prabotulinumtoxinA-xvfs for Injection

Evolus Inc announces that the US Food and Drug Administration has approved its lead product, Jeuveau, for the temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in adults.

David Moatazedi, president and chief executive officer of Evolus, states, “Evolus is the first company in nearly a decade to enter the fast-growing US aesthetic neurotoxin market. What makes Evolus unique is our focus on delivering performance beauty products with a customer-centric approach. We are pleased to introduce Jeuveau, the first FDA approved neurotoxin dedicated to aesthetics and manufactured in a state-of-the-art facility using Hi-Pure technology.”

To read the full press release, including safety information, visit globenewswire.com

Volume Loss, Not Just ‘Sagging,’ Causes Upper Lip Aging

Are aging-related changes in the face related more to “deflation” or “sagging”? A new study helps settle the debate, showing significant loss of volume in the upper lip in older adults, reports the February issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons (ASPS).

“Our results suggest that the aging perioral area is affected with a combination of soft tissue lengthening, thinning, and volume loss,” concludes the new research, led by Patrick L. Tonnard, MD, PhD, of Coupre Centre for Plastic Surgery, Ghent, Belgium. For plastic surgeons, the findings may help to inform and improve evidence-based approaches to facial rejuvenation.

The researchers analyzed magnetic resonance imaging (MRI) scans of the head obtained for other reasons in 200 adults: 100 women and 100 men. Participants were divided into a younger group aged 20 to 30 and an older group aged 65 to 80. Detailed measurements of the “upper lip unit” were analyzed to evaluate differences between the two groups, with an average age difference of nearly 50 years.

The measurements revealed several age-related differences in the anatomy of the upper lip. These included significant lengthening of the upper lip in older adults: about 19 percent longer in women and 18 percent longer in men, compared to the younger group.

The older group also had decreased soft tissue thickness of the upper lip: by about 41% in women and 33% in men. Most of the reduction in tissue thickness occurred at the “alar nasolabial fold” – the top of the lines running from the base of the nose to the corners of the lips.

The findings suggest that age-related lengthening and thinning of the upper lip represents more than just “sagging.”

“[V]olume loss is an obvious feature of the aging upper lip,” Tonnard and colleagues write. Loss of soft tissue volume also seems to contribute to deepening of the nasolabial folds, a prominent feature of the aging face.

“The mouth and perioral area play a primary role in emotional expression and attractiveness of the face,” according to the authors. “Unfortunately, the mechanisms of centrofacial aging are poorly understood” – as illustrated by the debate over “sagging versus deflation.”

The new study provides insights into these mechanisms, based on detailed MRI measurements in a large sample of older versus younger adults.

Lengthening, thinning, and volume loss all contribute to aging of the area around the mouth, the study suggests. The findings add to the evidence base underlying plastic surgery and other cosmetic procedures for facial rejuvenation.

Tonnard and colleagues plan a follow-up article to discuss the clinical implications of their findings, including the role of dermal fillers for minimally invasive volume augmentation.

[Source(s): Wolters Kluwer Health, EurekAlert]

Modern Thread Lifts Are No Longer Just for the Face

Dubbed a quick fix for hoisting up cheeks and jowls without the need for a surgical facelift—“threads,” aka sutures, are inserted into the skin via a needle—the original thread lifts quickly fell out of favor with the rest of the  country in 2002 when the barbed polypropylene threads often resulted in facial distortion and asymmetries. Some even broke under the skin, causing infections, or protruded through thinning skin in aging patients.

In 2015, Silhouette InstaLift spearheaded the shift from permanent, polypropylene threads to dissolvable, poly-l-lactic acid (PLLA) sutures. Brands such as Nova Threads and MINT have also introduced similar versions made of polydioxanone (PDO).

These modern thread lifts—many experts are moving away from the term “thread lift” and toward “absorbable suture suspension” to shake the stigma associated with old-school methods—also provide more than just a lifting benefit.

Dermal Micro-Coring May Make Nonsurgical Facelifts a Reality

A new technology currently in clinical trials could soon make our “knife-free facelift” fantasies a reality.

From the Boston-based biotech company Cytrellis comes the world’s first dermal micro-coring device, an energy-free needling tool that mechanically drills out minuscule columns of skin—each less than half a millimeter in diameter—in a fractional pattern across the mid and lower face, scarlessly removing 5 to 7.5 percent of the total surface area to shrink the skin overall.

Read the full article at www.newbeauty.com

New Surgical Technique Aims to Rejuvenate the Jawline

Extended Deep Plane Facelift Patient Before & After: This middle aged woman had an extended deep plane facelift procedure performed by Dr. Andrew Jacono, which included the restoration of the extended arc of a youthful jawline. (Image courtesy of New York Center for Facial Plastic & Laser Surgery)

Extended Deep Plane Facelift Patient Before & After: This middle aged woman had an extended deep plane facelift procedure performed by Dr. Andrew Jacono, which included the restoration of the extended arc of a youthful jawline. (Image courtesy of New York Center for Facial Plastic & Laser Surgery)

In a new study published in Aesthetic Surgery Journal, Andrew Jacono, MD, FACS, and director of the New York Center for Facial Plastic & Laser Surgery, unveils an advanced surgical technique that he suggests could help restore the youthful arc of a feminine jawline.

The study focuses on repositioning excess soft tissue to the back portion of the jaw to restore the contour and volume that creates the arc of a youthful feminine jawline. As we age, soft tissues of the face droop, creating jowls that hide the jawline while there is also a loss of volume over the jaw towards the ear, making the jawline appear shorter and puffier. Until now, facelifts have focused on rejuvenating the fallen jowls, failing to restore the extended arc of a youthful jawline which has come to represent an integral part of the feminine ideal.

In this study, this “arc” is defined as the Mandibular Defining Line (MDL), a new anatomic metric in evaluating the continuous, lower jawline contour from the chin to under the ear. The technique produces a 2.8 cm increase in length of the jawline, on average, re-lengthening the jawline that becomes truncated with age, explains a media release from the New York Center for Facial Plastic & Laser Surgery.

“Although today’s facelifting methods are able to remove jowls, the well-defined lower jawline of youth is not recreated. An easy way to pinpoint someone’s age regardless of whether they have undergone a facelift is to look at the length of their jawline,” Jacono says. “With this new technique, we now have the ability to create a defined, plush jawline from chin to ear. This adds length to the natural arc of youth, thus extending the MDL.”

The study included 203 consecutive patients that underwent extended deep plane facelifts with rotational flap modification. There was a mean increase in the length of the MDL from 7.1 cm preoperatively to 9.9 cm postoperatively. Postoperative imaging was performed using the VECTRA M3 Imaging System, which creates lifelike, high-resolution, three-dimensional renderings of aesthetic procedures, per the release.

[Source(s): New York Center for Facial Plastic & Laser Surgery, PR Newswire]

How Microneedling Eye Patches Made Me Look Much Less Tired

Putting tiny needle plasters anywhere near your eye region sounds torturous, but microneedling patches were actually originally designed as a more comfortable, long-term strategy for delivering drugs through the stratum corneum rather than via an injection.

Medical innovation has now made its way to the skincare aisles, with microneedle delivery coming to the fore to encourage the absorption of the hydrating yet tricksy hyaluronic acid especially.

Here’s how they work and why they’re perfect for a post-party lift…

Why Is Everyone Getting Botox Over the Holidays — and Where?

Summer has its influx of Rosé. October has pumpkins. The holiday season has stress, debt, and . . . Botox appointments?

According to recent data by payments company Square, it’s true: the time between Thanksgiving and New Year’s sees a consistent spike in Botox and filler procedures each year, but its biggest boom in sales yet has been in 2018 — up 65 percent compared to last year’s 44 percent.

AAFPRS Members Reveal Plastic Surgery Predictions for 2019

Facial plastic surgeons take out their crystal balls and share a glimpse of what we will see more, or less of, in the coming year in cosmetic surgery.

After taking a look into their crystal balls for the year ahead, American Academy of Facial Plastic and Reconstructive Surgery members reveal the following predictions:

Natural-looking results are here to stay.

Gone, but not totally forgotten are the highly sculpted noses, plumped-out puckers, and frozen faces of plastic surgery past. Today’s procedures create natural-looking results so you look refreshed, relaxed, and like the best version of yourself. As the memories of that over-done look fade to black, we can expect an even greater uptick in the number of men and women seeking cosmetic enhancements.

“The desire to look better, but natural, is not new. In fact, most patients fear the stretched or windblown look as well as the overdone, un-natural-looking nose. Overdone Hollywood celebrities do more to create fear of surgery. The biggest challenge for well-trained facial plastic surgeons is to help patients understand that they can have improvements, while looking totally normal, just better,” says Phillip R. Langsdon, MD, Memphis facial plastic surgeon and president of the American Academy of Facial Plastic & Reconstructive Surgery (AAFPRS), in a media release.

“The pendulum is swinging back to a more natural look,” adds Nashville facial plastic surgeon Mary Lynn Moran, MD, the president-elect of the AAFPRS. “We will see less overfilling of cheeks and lips in the coming year.”

Micro will be a macro buzz word in 2019.

Microneedling with platelet rich plasma (PRP), microblading, and micro- or baby Botox will gain momentum in the coming year. Microneedling uses a special roller or device with needles to create tiny channels in the skin to trigger its natural wound-healing capabilities, namely the production of collagen and elastin, the building blocks of supple, youthful skin.

PRP injections jump-start this healing response. Microblading is the new go-to for over-plucked or waxed eyebrows. It’s a type of tattooing where pigment is implanted under the skin with a manual handheld tool. Micro-Botox involves injecting small amounts of neuromodulator within the upper layers of the skin to enhance tone, smooth wrinkles, and reduce the size of pores.

Minimal tweaks combined can produce maximum results.

And we can except social media, selfie-awareness, and the recently coined “snapchat dysmorphia” to continue to fuel consultations and requests for facial plastic procedures in the coming year. In 2017, 55% of facial plastic surgeons noted having seen patients expressing a desire to look better in selfies, and this will has only gotten more pronounced.

“While there is definitely more interest because of social media, there is also a growing misconception of what can be realistically improved as well as how those improvements might be attained,” Langsdon comments, the release continues.

“Society is extremely self-critical as a result of social media pressure to live curated photo-documented lives, and this is not going to ease up,” Moran states.

Expect a greater emphasis on jawline aesthetics as a result. In the past, surgery was the only way to soften or sharpen a jawline, but now there are a host of minimally invasive techniques including injections, thread lifts, and energy-based treatments available to help taper the lower face. Combination therapies can offer more visible results with minimal intervention and manageable downtime.

[Source: Kelz PR]

The Fascinating Way Actors Coordinate Botox Appointments While Filming Movies

Botox in Hollywood is sort of like an all-black wardrobe in New York City: normal by way of sheer volume, and therefore completely unavoidable. Still, now more than ever, people across the country are seeking authenticity — in beauty ads, on social media, and on the big screen — which, for working actors, presents a dilemma.

How can someone with a smooth (read: Botoxed) forehead also make their surprise-face or ugly-cry look believable on TV or a movie? Turns out, the answer all comes down to timing, puppeteered by the actor, a dermatologist, and the film crew.

Your Guide to At-Home Derma Rollers

Derma rollers are an interesting – and yep, scary – beauty product. At a glance, the idea of pin-pricking your skin with tiny needles seems painful and confusing. How can that possibly do your skin any good? Well, there is a method to the madness.

A derma roller is a hand-held device that features hundreds of micro-needles around the circumference of its roller head. It’s like a mini paint roller with needles. When rolled over the skin, the needles create micro-injuries that signal to your body to produce more collagen and elastin to repair the affected area. It may also help heal scars (including acne scars). The concept is the same as the professional version – microneedling,